“Illinois researchers have combined two molecular imaging technologies to create an instrument with incredible sensitivity that provides new, detailed insight into dynamic molecular processes.
Physics professors Taekjip Ha and Yann Chemla combined their expertise in single-molecule biophysics—fluorescence microscopy and optical traps, respectively—to study binding and unbinding of individual DNA segments to a larger strand. They and their joint postdoctoral researcher Matthew Comstock detail their technique in a paper published in the Feb. 20 online edition of Nature Methods.”
Illinois researchers developed a new technique that combines
optical traps (red) with fluorescence (green)
to study the proteins that regulate DNA.
Image by Matthew Comstock, University of Illinois
Read the full article here.