From HFCC at WCG: “Help Fight Childhood Cancer Project Researchers Publish a Paper”

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6 Jun 2016

Summary
The Help Fight Childhood Cancer project searched for a cure for a particular childhood brain cancer. The researchers have found that some of the promising compounds they identified also show an antidepressant capability.

Lay Summary:

The Help Fight Childhood Cancer project researchers have published a paper on serendipitous results they found from the drug candidate search run on World Community Grid. The project originally searched for candidate compounds that targeted specific proteins to help cure a childhood brain cancer called neuroblastoma. Some of the targeted proteins are also involved in several psychological disorders. They have found that some of the identified compounds show an antidepressant capability. Furthermore, additional research might lead to potential treatments for Huntington’s disease and Alzheimer’s disease. The paper was published in the journal Neurochemistry International.

Paper title: Effects of novel small compounds targeting TrkB on neuronal cell survival and depression-like behavior

Authors: Mayu Fukuda, Atsushi Takotori, Yohko Nakamura, Akiko Suganami, Tyuji Hoshino, Yutaka Tamura, Akira Nakagawara

See the full article here.

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