July 17, 2013
Glenn Roberts Jr
“A new screening program will allow researchers to quickly confirm whether precious biological samples yield useful information when struck by the intense X-ray pulses at SLAC’s Linac Coherent Light Source (LCLS).
Marc Messerschmidt, a staff scientist who leads the Protein Crystal Screening Program at the Linac Coherent Light Source (LCLS) X-ray laser, works at the Coherent X-ray Imaging (CXI) experimental station. (Matt Beardsley)
The Protein Crystal Screening Program opens up multiple 6-hour shifts at LCLS to both newcomers and returnees. It has two goals: to broaden access to LCLS and to improve the success and productivity of X-ray crystallography experiments during regular runs of more extended experiments, which are in such high demand that fewer than one in four proposals can be accepted.
Tiny crystallized protein samples are streamed across X-ray laser pulses and the diffracted light patterns are recorded by a high-resolution detector, at bottom, in this illustration of a crystallography experiment at SLAC’s Linac Coherent Light Source X-ray laser. (Greg Stewart)
Twenty-eight crystal screening slots are already scheduled for October 2013 through March 2014, and new proposals are now being sought for a batch of 20 screening shifts for the next LCLS run, which begins in April 2014. The deadline for those proposals is Oct. 22.
‘This screening is potentially giving you an edge in telling you how to focus your time and effort to get the most out of an experiment,’ said SLAC’s Marc Messerschmidt, an LCLS staff scientist who leads the upstart program.”
See the full article here.
SLAC is a multi-program laboratory exploring frontier questions in photon science, astrophysics, particle physics and accelerator research. Located in Menlo Park, California, SLAC is operated by Stanford University for the DOE’s Office of Science.
ScienceSprings is powered by MAINGEAR computers